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The accumulated tissue changes in long-standing injuries mean more extensive remodeling is necessary for functional improvement

For muscle, joint, tendon, or ligament support, injections may be considered more targeted because they enter the body more directly

pediatric and intranasal regimens are detailed in specialized dosing references and should be individualized

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Inflammopharmacology 7:114 Lovric-Bencic M, Sikiric P, Hanzevacki JS, Seiwerth S, Rogic D, Kusec V, Aralica G, Konjevoda P, Batelja L, Blagaic AB (2004) Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse