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Without sufficient protein, a significant proportion of weight loss may come from muscle tissue rather than fat, potentially compromising physical function and increasing the risk of weight regain

Patients taking oral contraceptives may need to use backup contraception for a short time after starting or increasing the dose

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The first month of compounded tirzepatide injections through MEDVi costs $279

The mild ketosis associated with weight loss on semaglutide is generally benign and indicates effective fat metabolism