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Name: benefits of glp-1 beyond weight loss GLP-1: Health Effects GLP-1 medications like semaglutide and
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Piccini S, Favacchio G, Panico C, Morenghi E, Folli F, Mazziotti G, et al

doi: 10.1186/s12920-023-01666-w 248 RiveraCAWheelerMDEnomotoNThurmanRG

Some variants have clear structural explanations for their loss-of-function, for example, variants can disrupt binding of carnitine (R471C/H/P), affect the Na + -binding site (N32S), disrupt the TM2-TM11 H-bonding network (S467C) or perturb gating residues conserved in OCTs/OATs (R169Q/P/W)