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By occupying these receptors, spironolactone reduces sebum output by up to 30 to 50% at doses between 50 and 200 mg daily 1

It can also benefit mood and cognitive function by increasing levels of GABA and dopamine

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1 Improved Blood Glucose Control: GLP-1 agonists can reduce HbA1c (a marker of average blood glucose levels over 3 months) by around 1% to 2%, which is comparable to or even exceeds other diabetes treatments