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The study showed that compared with non-targeted liposomes (Lip-EXT), the cellular uptake rate of Apt-Lip-EXT was increased by approximately 97%, the in vitro transport efficiency was increased by approximately 95%, and absorption in small intestinal Peyers patches was significantly enhanced, indicating that aptamer modification can effectively promote M cell-mediated transport and targeted delivery of liposomes ( 2.3 Small-molecule ligand modification In oral liposome delivery systems, to overcome GI barriers and improve drug absorption efficiency, researchers have widely used small-molecule active substances as targeting ligands to modify the liposome surface for active targeting

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Reported research observations describe two proposed activities under controlled experimental conditions: stimulation of lipolysis (the breakdown of stored triglycerides in adipocytes) and inhibition of lipogenesis (the conversion of non-fat substrates into stored fat)

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