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Patient safety advice : If you experience persistent or severe abdominal pain (with or without vomiting), seek urgent medical attention and withhold further doses until assessed by a healthcare professional, as these symptoms may indicate pancreatitis

A negative sodium balance is obtained by reducing sodium intake and enhancing sodium excretion with the use of diuretics

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Evidence for genetic abnormalities in fibromyalgia has also been elucidated, with family studies showing that first-degree relatives of individuals with FMS display an eight-fold risk of developing the syndrome as compared to family members of patients with rheumatoid arthritis (RA)