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Underlying conditions that can impair treatment response include hypothyroidism, polycystic ovary syndrome (PCOS), Cushing's syndrome, obstructive sleep apnea, and psychiatric conditions like binge eating disorder

In a previous Phase I trial, six patients treated with a single dose of NTLA-2001 showed significant reductions in serum TTR protein levels, with no serious adverse effects or liver damage reported

To prevent muscle and bone loss, people on these medications should prioritize protein and regular resistance training in their daily routine

These facilities meet strict federal and state requirements, follow rigorous quality and sterility standards, and are regularly inspected by the FDA

In the subsequent experiments, we concentrated on the 60 genes that met the previously mentioned criteria and conducted an analysis