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Description

Strikingly, among the three LEO-upregulated SCFAs (acetic acid, isobutyric acid, butyric acid), only butyrate stimulated GLP-1 secretion in a concentration-dependent manner (30 M and 60 M

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Ciardullo S, Mantovani A, Morieri ML, Muraca E, Invernizzi P, Perseghin G

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Notably, TGF- is considered the master regulator of fibrosis, and its downstream signalling is transduced primarily through the phosphorylation and activation of receptor-associated Smads (R-Smads), Smad2 and Smad3

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