When the gut barrier is compromised, it allows lipopolysaccharides (LPS)toxic structural components found on the outer membrane of gram-negative gut bacteriato "leak" or translocate from the intestinal lumen directly into the bloodstream
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In contrast, DIO mice in both groups switched from WD to LD each had significantly increased Proteobacteria relative abundance (represented solely by the genus Parasutterella ) compared to both the WD and the LD controls, suggesting that Proteobacteria relative abundance may be largely influenced by stress or the differences in net energy expenditure (or associated body weight changes) caused by the diet switch
Cases of (rare) malignant hyperthermia have been reported
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