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produce acetate and propionate, which help to control immunological responses and reduce intestinal inflammation

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In relation to AT remodelling, it was shown that p53 signalling is induced in adipocytes upon obesity development in mice, causing adipocyte senescence, AT inflammation, and systemic insulin resistance 24,70

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Follow-up labs performed every three to six months allow clinicians to evaluate treatment response, guide dose adjustments, and monitor for potential adverse effects

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