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It has been demonstrated that patients with DRESS related to sulfonamides have, in many cases, a high incidence of slow acetylators carrier status (low N-acetylation), which determines N-acetyl-transferase deficiency, resulting in the formation of excessive amounts of hydroxylamine metabolites, which reach toxic levels and are capable of causing cell damage and immune activation.19 In Taiwanese, Japanese and Malaysian populations, a CYP2C9*3 gene variant (capable of reducing phenytoin excretion) is frequently found and is especially associated with DRESS triggered by this medication use

February 15, 2023

Well, its certainly disruptive, but the solution, from the insurers perspectives, is clear: Raise the cost of coverage, or at least the cost of insurance plans that cover these drugs

When appetite is suppressed, you have to be deliberate about hitting protein, since it is easy to drift into eating almost nothing and wondering why energy tanks

Keeping them in the fridge may be an ideal solution