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Mechanism of action Activation of MC4R in the medial preoptic area and paraventricular nucleus increases dopamine release in the mesolimbic pathway, which is thought to mediate libido and sexual response independently of peripheral blood flow

Lancet (London England) 403(10434):e21e31 Boggio Marzet C, Burgos F, Del Compare M, Gerold I, Tabacco O, Vinderola G (2022) Approach to probiotics in pediatrics: the role of Lactobacillus rhamnosus GG