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36 Results from the Semaglutide and Walking Capacity in People with Symptomatic Peripheral Artery Disease and T2DM (STRIDE) trial also found that semaglutide 1.0 mg once weekly is associated with an increase in walking distance in individuals with symptomatic peripheral artery disease and T2DM

For example, take one pill with breakfast and one with lunch

Inadequate protein or fibre intake: If meals are low in protein or dietary fibre, satiety signals may be weaker and shorter-lived, leading to hunger returning sooner than expected between meals

Recent reviews (published in January 2025 ) confirm that GLP-1 is a dual-action hormone

The trial enrolled 281 participants with type 2 diabetes who were randomized to receive 0.5 mg, 4 mg, 8 mg, or 12 mg doses of retatrutide, 1.5 mg of dulaglutide, or placebo for 36 weeks