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Two more recent studies investigating the risk of stroke in G6PD-d subjects in China concluded that G6PD-d was associated with significantly increased risk of large vessel atherosclerosis, stroke history, and intracranial atherosclerotic stenosis (ICAS) 20,21

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If reducing agents (DTT, TCEP, beta-mercaptoethanol) are present in the storage buffer, even at low concentrations, they will gradually cleave this bridge over time