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2.3 Study Design and Pharmacokinetic Sampling This was a multicenter, single-dose, open-label, parallel-group study (ClinicalTrials.gov identifier NCT00833716) conducted in accordance with Good Clinical Practice [32], the Declaration of Helsinki, and relevant guidelines for studies in patients with RI [33, 34]

24 October 2023

If you have documented atrial fibrillation, consider a 24-hour Holter monitor to establish baseline ectopic beat burden

Important Considerations Any cognitive enhancement strategy requires careful evaluation, especially when compounds may affect mitochondrial function, neurotransmitter systems, or neural growth pathways

although the difference in age range of the sample and the brain region studied makes difficult a direct comparison