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Lau, David C W
Fujiwara, A
doi: 10.5435/00124635-199903000-00003
Since the reducing potential of the cytoplasm of a bacterial cell and the cytosolic compartment of a plant cell or a eukaryotic cell often precludes the widespread formation of thermodynamically stable disulfide bonds (see below), a metal ion like Zn II , which is stable in the 2 + oxidation state and refractory to oxidationreduction chemistry, can perform such a function
Key finding: AOD 9604 reduced cartilage damage score by 67%, decreased MMP-13 activity by 58%, and preserved joint space width
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