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Those with growth hormone deficiencies or age-related health issues may benefit from IGF-1 therapy under medical supervision

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It prevents free radicals, heavy metals, lipid and non-lipid peroxides and other reactive oxygen species from causing damage to the most important components of the cells

Due to the complicating factor of a shot and the extra cost, it seems the best route for most people is to focus on getting adequate B vitamins from food, and supplement as necessary.