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Vitamin B12 deficiency has been linked to fatigue, tingling or loss of feeling in the extremities, irritability, memory impairment, depression, anemia, irritable bowel syndrome (IBS), constipation, poor wound healing, dry or damaged looking skin, and neurological disorders

de Groot, Robert Clarke, Jrn Schneede, Per M

Why the off phase matters: continuous dosing flattens pituitary response over time

PMID: 30915550 Malinda KM, et al

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