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Branched-chain amino acids (which are the essential amino acids valine, isoleucine, and leucine) stimulate muscle protein synthesis, potentially more than a normal protein on its own

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A limitation of the current study is the absence of measurement of serum GnRH levels and hypothalamic-pituitary axis, which should be addressed in follow-up research

115 , 116 The guidelines for diagnosis and management of the cobalaminrelated remethylation disorders recommend treatment with parenteral hydroxylcobalamin in suspected cases of remethylation disorder, the incidence of serious complications, and for significant improvement in patient survival

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