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When pH drops below 5.5, carboxyl groups (COOH) protonate, causing polymer contraction, which compresses internal pores and expels molecules ( - ), these systems exhibit synergistic antimicrobial-remineralizing dual functionality, presenting a promising strategy for secondary caries prevention and therapy ( 2.1.1 BioUnion BioUnion filler is a novel bioactive glass powder ( 2 ), zinc oxide (ZnO), calcium oxide (CaO), and a fluoride compound

Key organs like the liver filter blood and neutralize chemicals, while the kidneys remove waste through urine

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Inhibition of CYPs by ABT strongly increased the nephro- and hepatotoxicity of OTA

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