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The gastrointestinal effects typically emerge during dose escalation and may diminish with continued use as physiologic adaptation occurs

As concomitant abuse of different drugs is common in todays society, the effects of GLP-1R agonists on the intake on multiple addictive drugs in a situation where the rats can choose between different drugs should be tested

For individuals managing chronic conditions such as diabetes, maintaining medication adherence whilst travelling is crucial for glycaemic control and preventing complications

Another option is new pills to treat obesity, which will be cheaper than their injectable counterparts