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Based on available research, GHK-Cu appears to be well-tolerated

Animal studies have found that BPC-157 appears to modulate dopamine receptor sensitivity and influence serotonin pathways in ways that produce antidepressant-like and anxiolytic-like behavioral outcomes in standardized animal behavioral tests

Abstract 13840: safety outcomes from a first-in-human study of a novel investigational monoclonal antibody, REGN5381, an agonist to the natriuretic peptide receptor 1