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Mechanism of Action Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RAs) are a class of medications that mimic the natural hormone GLP-1, produced by the small intestine (23)

Of additional importance, the available evidence indicates that JWU-A021 is one of the most potent non-electrophilic TRPA-1 channel agonists yet to be reported in the literature

doi: 10.1016/j.neuro.2013.07.010 8 BjrklundG.ShanaidaM.LysiukR.AntonyakH.KlishchI.ShanaidaV.et al

If diarrhea persists beyond 8 weeks or worsens, contact your healthcare provider to discuss dose timing, escalation pace, or alternative medication formulations available through PlexusDx

Alan Gaby's monograph on the Myers is still the "bible" on the therapy - discussing numerous case reports