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A new treatment strategy for Parkinsons disease through the gut-brain axis

The research utilized male Sprague-Dawley rats and various in vitro and ex vivo experimental models

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It binds to ghrelin receptors in the pituitary through a completely separate mechanism

In the last decade, studies on the condition of BBB in neurodegenerative diseases, including ALS, have demonstrated the presence of vascular disruption, a condition that could theoretically favour the entry of drugs into brain regions affected by neurodegeneration