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This flexibility allows patients to carry their pen or vial without constant refrigeration access during travel or daily activities

This includes changes in health, medications, or diet

While the benefits of single antioxidant therapy may be limited and may even have negative effects, for example, long-term use of beta-carotene may increase the incidence of lung cancer in smokers (60), while vitamin E may increase the risk of bleeding in people with oral anticoagulants and even reduce the lipid-lowering effect of statins (61), Therefore, the safety and efficacy of long-term additional oral antioxidants deserve further exploration

Acta 191 , 541549 (1969)

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