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Contrave produced greater improvements in various cardiometabolic risk markers, participant-reported weight-related quality of life, and eating control

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Subsequently, GLP-1s gained FDA approval for weight loss in 2014 (liraglutide: Saxenda/Victoza), 2021 (semaglutide: Wegovy/Ozempic/Rybelsus), and 2023 (tirzepatide: Zepbound/Mounjaro)

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Hoffmann-La Roche Ltd was involved in the study design, collection, analysis, interpretation of data, the writing of this article and the decision to submit it for publication

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