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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist drug, FDA-approved for type 2 diabetes mellitus (Ozempic and Rybelsus) and chronic weight management (Wegovy)

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There are nine identified forms of 3-methylglutaconic aciduria (MGCA1 to MGCA9), but only MGCA1 is associated with direct deficiency in leucine catabolism

A typical program lasts approximately four to six weeks