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Anxiety-like behavior can be induced in rats through intracerebroventricular streptozotocin (ICV-STZ) injections, which is accompanied by diffuse amyloid plaques in the hippocampus, enlargement of ventricles, and spine loss in the dentate gyrus (Roy et al., 2022)

Chronic oral inflammation correlates with insulin resistance and neurodegeneration

Jun 2004;29(3):226-31