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The result is oxidative stress (OS) which is linked to numerous disease processes including cognitive decline (Alzheimers disease) and other age-related conditions like cancer, cardiovascular disease, and diabetes

Impact of dietary selenium on modulation of expression of several Non-Selenoprotein genes related to key ovarian functions, female fertility, and proteostasis: a Transcriptome-Based analysis of the aging mice ovaries [J]

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therefore, adopting strategies to minimize muscle and bone loss is prudent