Cycled Protocol Design Epithalon is typically dosed in cycled protocols (often 10-20 day cycles 1-2 times per year), supporting flexible integration with other longevity protocols
Reported biochemical potency against human NNMT is in the low-micromolar range with cellular EC values in the low-micromolar range for suppression of 1-MNA and lipogenesis, with selectivity over related methyltransferases and NAD-salvage enzymes [1,6,7]
It consists of good fats and a little collagen, so the glow becomes the new normal every day
[11] Additionally, Rich suggested avoiding choline or TMG supplementation, as it could push the BHMT pathway at the expense of the methionine pathway, and to avoid over-supplementing with different forms of folate that would compete for absorption
We view the shortage of GLP-1s to be much worse than the official data suggests