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ALDH2*2 carriers have a high risk for esophageal cancer even with less ethanol consumption [4,6,7] and ALDH2*2 is also associated with osteoporosis [8], Alzheimers disease [9,10], and coronary artery spasm in relation to tobacco smoke exposure [11]

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doi: 10.1111/jdi.13115

Semaglutide might make you forget to drink, while creatine requires extra water to be effective