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Apolipoprotein e and alzheimers disease: the influence of apolipoprotein e on amyloid-beta and other amyloidogenic proteins

CHO R C5 drug resistant cells show high P-gp expression relative to drug sensitive AuxB1, or P-gp-knockout cells (AuxB1 Pgp , CHO R C5 PgpA1 , and CHO R C5 PgpA3 )

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These compounds are widely discussed in medical literature for roles related to cellular repair signaling, angiogenesis (formation of new small blood vessels), collagen and extracellular matrix remodeling, and support of normal inflammatory responses

Here, we summarize data supporting the use of GLP-1RAs for the treatment of neurodegenerative diseases, with a focus on AD