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In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis

One reconstitution event reduces aseptic-technique risk, one fridge slot instead of three, and a fixed ratio for protocols where the ratio is held constant

Regular maintenance treatmentstypically monthly or bi-weeklyhelp sustain optimal levels and ongoing benefits