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Within experimental contexts, it is evaluated for potential effects on endogenous growth hormone signaling through receptor-mediated mechanisms associated with pulsatile hormone release dynamics

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To determine dose level and dose frequency of central administration of mGIPR-Ab, pharmacokinetic profile of ( a ) brain and ( b ) plasma exposure was assessed at 4, 24, 72, 120, and 168 h following a single ICV injection of 15 g/L/mouse dose of mGIPR-Ab

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