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Sensitivity of KRAS mutant colorectal cancers to combination therapy that co-targets MEK and CDK4/6

The intracellular metabolite extracts and 2 mL of spent culture medium containing extracellular metabolites were freeze-dried (BenchTop K manifold freeze dryer, VirTis) prior chemical derivatisation

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However, the judges questions suggested that at least some members of the panel were concerned that the district court may have applied the federal expert testimony standards too aggressively