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Direct answer: GLP-1 receptor agonists affect glucose regulation, appetite, and digestion

If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy

AOD-9604 is not FDA-approved for any indication, and all use represents off-label application requiring informed medical decision-making

Geriatric use: Elderly patients may be more sensitive to NSAIDs, so it is recommended to use the lowest effective dose

These areas are more sensitive to lipolytic stimulation than male fat distribution patterns, which tend to concentrate centrally