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An argument has been made that duodenal secretion of GLP-1 is responsible for early phase GLP-1 secretion (222) but no direct link has been found

Talk to your doctor about all the medications included in your treatment plan to make sure you understand potential side effects and are prepared to quickly report them to your doctor should they occur

Effects of GLP-1 and GIP receptor agonists include: Stimulating insulin secretion in response to food (glucose-dependent) Reducing inappropriate glucagon release, lowering hepatic glucose output (GLP-1 enhances the sensitivity of alpha cells to glucose , resulting in more glucose-appropriate glucagon secretion) When blood glucose is high, insulin secretion is stimulated and glucagon secretion is inhibited

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