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Beyond direct -cell protection, butyrate exerts indirect protective effects by modulating immune responses and promoting the differentiation of Tregs that shield pancreatic -cells from cytokine-induced damage (189, 190)

See links to the relevant research below

Data from the studies analyzed suggested a potential role for several antioxidant molecules including vitamin D, vitamin E, vitamin A and melatonin

That second molecule can turn on some special activity by the cell

For example, SCFAs regulate inflammation, oxidative stress, and fibrosis and have been involved in kidney disease by activating the gut-kidney axis (Li et al., 2017