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I am a huge fan of DAO enzymes diamine oxidase enzymes because histamine at the gut level causes intestinal permeability and triggers dendritic activation

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Metformin contains no GLP-1 activity whatsoever, making it fundamentally different from modern peptide-based therapies that directly target appetite centers in the hypothalamus

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Semaglutide (Ozempic, Wegovy) is a GLP-1 receptor agonist that must be refrigerated at 36F to 46F (2C to 8C) before first use to maintain its effectiveness