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2021R1A2C2008519, 2022R1C1C2002949, and 2022R1A5A6000760]

Esto significa que la va del GLP-1 ya est activa en el intestino y que su eficacia depende en parte de la composicin del microbioma

For example, switching from morning to evening (or vice versa) changes when peak medication concentration aligns with food intake and activity levels, potentially reducing symptom severity

For people with metabolic syndrome or multiple cardiovascular risk factors, this broader metabolic improvement is potentially more important than the weight loss itself

doi: 10.3389/fnut.2026.1711478 Received 23 September 2025 Revised 03 February 2026 Accepted 11 February 2026 Published 11 March 2026 Volume 13 - 2026 Edited by Patrick Nol Pallier, Queen Mary University of London, United Kingdom Reviewed by Alexander P