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Statistical significance was assessed using one-sided ANOVAs followed by Sidaks and Dunnetts ( c , d ) multiple comparisons adjustments, paired t- tests ( e ), repeated measures two-sided ANOVAs followed by Dunnetts multiple comparisons adjustment ( f ), KruskalWallis tests followed by Dunns multiple comparisons adjustment ( g , h , i (Y3.3)), or Welchs one-way ANOVA followed by Dunnetts T3 multiple comparisons adjustment ( i (Y1.7))

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6 This rise is expected to be at least partially due to the increasing size of high-risk minority populations and the aging of the population

In July 2025, following the CVS formulary change, 9.6% of patients on AOM tirzepatide switched to a different drug

What this means practically: you cannot treat $89/month as your all-in monthly cost for GLP-1 treatment