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doi: 10.1016/j.chest.2017.03.056 81 GardinerPWikellCCliftonSShearerJBenjaminAPetersSA

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Topical vs systemic administration in research In dermatological research GHK-Cu is used topically (creams, gels, masks) at concentrations of 0.1 to 2 %

and Bifidobacterium app., along with increased abundance of pro-inflammatory taxa including Clostridioides difficile (Pessa et al., 2023), reduced differentiation of Tregs, and exaggerated Th2-type immune responses, all of which contribute to heightened skin sensitivity and inflammation (Pan et al., 2023