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Your levels of this antioxidant can be depleted due to many factors, such as aging, diet, and a sedentary lifestyle

They may recommend reducing the dose or trying an alternative treatment to achieve better bowel regularity while still managing your blood sugar levels effectively

Notably, while the global prevalence of diabetes is estimated to surge by 46% in 2045, the prevalence in Southeast Asia alone is expected to increase by 68% within the same period [1]

This imbalance renders granulosa cells vulnerable to ferroptosis, which can impair estrogen synthesis and disrupt follicular development ( - expression and promoting lipid peroxidation, ultimately triggering ferroptosis ( Notably, androgen excess, a hallmark of PCOS, may also contribute to ferroptosis

Up-regulated expression of WNT5a increases inflammation and oxidative stress via PI3K/AKT/NF-B signaling in the granulosa cells of PCOS patients