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From a pathophysiological perspective, my first thought is that this could reflect an indirect effect on peripheral nerve sensitivity, possibly related to: rapid shifts in glucoselipid metabolism, changes in nerve conduction due to electrolyte fluctuations, or even a centrally mediated effect, considering GLP-1 receptor expression in the CNS

Many of the most popular Body Positivity role models only have imperfect bodies when they take off their clothes and draw arrows pointing to their imperfections, writes National Association to Advance Fat Acceptance chair Tigress Osborn for the BBC

Rare but severe side effects include digestive, kidney, and thyroid issues, hair loss, rapid heart rate, vision problems, and mental health concerns