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In a bid to re-establish homeostasis, these elevated danger signals, often released by neurons at the developing epileptogenic site, instigate pro-inflammatory responses through detection by pattern recognition receptors (PRRs) such as Toll-like (TLRs) and Nod-like (NLRs) immune receptors [47]

[DOI] [PubMed] [Google Scholar] 5.Pachner AR, Steiner I

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The entire explant is imaged for all antibody and nuclear labeling in a 3-dimensional X-Y-Z plane in which the Z-plane consists of a stack imaged at intervals of 0.5-5 m