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In relation to histamine, methylation is required for the HNMT enzyme (which breaks down histamine in the brain) and COMT enzyme (which detoxifies oestrogen in the liver)

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The dietary supplement health and education act: time for a reassessment: comment on acute selenium toxicity associated with a dietary supplement. Arch Intern Med

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He K, Li Y, Guo X, Zhong L, Tang S (2020) Food groups and the likelihood of non-alcoholic fatty liver disease: a systematic review and meta-analysis