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This combination of theoretical and practical approaches enables a deeper understanding of the injury mechanisms and helps in developing more effective prevention and rehabilitation strategies

Study course: In rats, a procedure of ureter ligation was performed, which led to hydronephrosis, development of fibrosis, damage to tubular cells, and interstitial inflammation

ROS are signaling molecules that induce the release of pro-inflammatory cytokines [6], and the dysregulation of this response plays an essential role in the development of inflammation [7]

This work was supported in part by grants from the National Key R&D Program of China (No

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