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Methods In order to gain insights into the molecular pathways underlying progression of emphysema and explore computational strategies for identifying COPD therapeutics, we profiled gene expression in lung tissue samples obtained from regions within the same lung with varying amounts of emphysematous destruction from smokers with COPD (8 regions 8 lungs = 64 samples)
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Wegovy is a peptide that undergoes proteolytic degradation, whilst Prozac is metabolised primarily by the hepatic cytochrome P450 system (particularly CYP2D6)
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