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Description

Consistently, in another in vivo/in vitro study using a rat transient MCAO model, exendin-4 reduced BBB tight-junction protein degradation by inhibiting MMP-9 activation and reactive oxygen species (ROS) production via activation of the Wnt/-catenin signaling pathway [64]

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Additional contraceptive methods are recommended for 4 weeks after starting Mounjaro and after each dose increase

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Grundy SM, Cleeman JI, Merz CN, Brewer HB Jr, Clark LT, Hunninghake DB, Pasternak RC, Smith SC Jr, Stone NJ

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This broad transcriptional effect is unusual for a tripeptide and has attracted significant research interest

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