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Together, these finding indicate that the toxic effects of DOX on the heart are strongly associated with iron overload and ferroptosis in mitochondria, indicating that targeting ferroptosis could serve as a promising therapeutic strategy for protecting the hearts of cancer patients from DOX-induced cardiomyopathy

The mutations might be present on genes depending on the specific cell types and states, and these genes may exhibit varying levels of co-expression throughout embryonic brain development

Following intraperitoneal administration in rat models, BPC-157 increased serotonin synthesis in the substantia nigra reticulate and medial anterior olfactory nucleus

World J Cardiol (2014) 6:46277